We recommend refrigerating FlowFlora, especially for those in hotter climates.

Don't take FlowFlora if you are immunocompromised, have had recent surgery or are seriously ill. Talk to your Doctor first if you are pregnant.

Lactobacillus Acidophilus LA-14®
1. Elawadli I, Brisbin JT, Mallard BA, et al. Differential effects of lactobacilli on activation and maturation of mouse dendritic cells. *Beneficial Microbes*. 2014;5(3):323-334.

2. Paineau D, Carcano D, Leyer G. Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial. *FEMS Immunol Med Microbiol*. 2008;53(1):107-113.

3. Bertuccini L, Russo R, Iosi F, Superti F. Effects of Lactobacillus rhamnosus and Lactobacillus acidophilus on bacterial vaginal pathogens. *Intl J Immunopathology Pharmacology*. 2017;30(2):163-167.

4. Jang SE, Jeong JJ, Choi SY, et al. Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus La-14 attenuate Gardnerella vaginalis-infected bacterial vaginosis in mice. *Nutrients*. 2017;9:531; doi:10.3390/nu9060531.

5. De Alberti D, Russo R, Terruzzi F, Nobile V, Ouwehand AC. Lactobacilli vaginal colonisation after oral consumption of Respecta® complex: a randomized controlled pilot study. *Arch Gynecol Obstet*. 2015;292(4):861-867.

Bifidobacterium lactis-04®
1. Bartosch S, Woodmansey EJ, Paterson JC, McMurdo ME, Macfarlane GT. Microbiological effects of consuming a synbiotic containing Bifidobacterium bifidum, Bifidobacterium lactis and oligofructose in elderly persons, determined by real-time polymerase chain reaction and counting of viable bacteria. *Clin Infect Dis*. 2005;40:28-37.

2. Ouwehand AC, Nermes M, Collado MC, et al. Specific probiotics alleviate allergic rhinitis during the birch pollen season. *World J Gastroenterology*. 2009;15.

3. Turner R, Woodfolk J, Borish L, et al. Effect of probiotic on innate inflammatory response and viral shedding in experimental rhinovirus infection – a randomised controlled trial. *Beneficial Microbes*. 2017;8:207-215.

4. West NP, Horn PL, Pyne DB, et al. Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individuals. *Clin Nutr*. 2014;33:581-587.

5. Ouwehand AC, DongLian C, Weijian X, et al. Probiotics reduce symptoms of antibiotic use in a hospital setting: a randomized dose response study. *Vaccine*. 2014;32:458-463.

Lactobacillus Plantarum Lp-115®

1. Paineau D, Carcano D, Leyer G, Darquy S, Alyanakian MA, Simoneau G, Bergmann JF, Brassart D, Bornet F, Ouwehand AC. Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial. *FEMS Immunol Med Microbiol*. 2008;53:107-113.

2. Barreto FM, Colado Simão AN, Morimoto HK, Batisti Lozovoy MA, Dichi I, Helena da Silva Miglioranza L. Beneficial effects of Lactobacillus plantarum on glycemia and homocysteine levels in postmenopausal women with metabolic syndrome.*Nutrition*. 2014 Jul-Aug;30(7-8):939-942. Epub 2013 Dec 14. - Also listed under Insulin sensitivity.**Insulin sensitivity**

3. Barreto FM, Colado Simão AN, Morimoto HK, Batisti Lozovoy MA, Dichi I, Helena da Silva Miglioranza L. Beneficial effects of Lactobacillus plantarum on glycemia and homocysteine levels in postmenopausal women with metabolic syndrome. *Nutrition*. 2014 Jul-Aug;30(7-8):939-942. Epub 2013 Dec 14. - Also listed under Cholesterol lowering.**General health**

4. Zhang Y, Chen J, Wu J, Chalson H, Merigan L, Mitchell A. Probiotic use in preventing postoperative infection in liver transplant patients. *Hepatobiliary Surg Nutr*. 2013 Jun;2(3):142-147.

Lactobacillus Paracasei Lpc-37®
1. Ouwehand AC, DongLian C, Weijian X, et al. Probiotics reduce symptoms of antibiotic use in a hospital setting: a randomized dose response study. *Vaccine*. 2014;32:458-463.

2. Patterson E, Griffin SM, Ibarra A, Ellsiepen E, Hellhammer J. Lacticaseibacillus paracasei Lpc-37® improves psychological and physiological markers of stress and anxiety in healthy adults: a randomized, double-blind, placebo-controlled and parallel clinical trial (the Sisu study). *Neurobiol Stress*. 2020;13:100277. doi: 10.1016/j.ynstr.2020.100277.

3. Ding WK, Shah NP. Acid, bile and heat tolerance of free and microencapsulated probiotic bacteria. *J Food Sci*. 2007;72:M446-450.4. Gibson GR, McCartney AL, Rastall RA. Prebiotics and resistance to gastrointestinal infections. *Br J Nutr*. 2005;93(Suppl. 1):S31-34.